I am writing a python code using Notepad++ and am noticing that when I tab comments to the right of the code they are not lining up visually on the screen. Looking at the column number of the first character of each comment it appears that the columns don't align visually with their column number.
You can see that the comments on line 48 and 49 both start at column 49 but look out of line. Is there a way to change this so all the columns line up?
I tried changing different texts in the style configurator but none seemed to fix the issue.

You have to use a font where all characters (including spaces) are same length wide, they are called monospace fonts.
One of most popular is
Courier new.