I sending over the Controller an JSON response
$response = new JsonResponse($array);
return $response;
When I call the controller direct over the browse there is a Status 200, but over an Ajax call Symfony don't receives any status. Here the screen of the debugging toolbar:
The problem was the AdBlocker. In my URL I had the keyword /advertiser/ and thats why the Adblocker has blocked the request.
Without Adblocker or changing the URL works fine!