Reduce noise by averaging images coming from x-ray camera (16 bit grayscale)

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I am getting 16 bit grayscale images from a camera. I want to reduce the noise of these images by averaging the images (by factor of 2, 4 etc).

I have the pixel data in a byte array. I have tried to use Aforge.Net,but the code throws exception when trying to apply noise reduction (AForge.Imaging.UnsupportedImageFormatException: 'Source pixel format is not supported by the filter.').

Is there a better way to apply noise reduction by averaging incoming images directly on a byte array?

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