There are various samples available for how to host Python or Ruby running on the DLR, inside your own AppDomain.
Are you able to do this yet with VB? There have been mentions of this since the DLR was announced 18 months ago, but I can't find a code sample for it.
Maybe with the PDC VS10 CTP? If so, what assembly contains the appropriate subclassed ScriptRuntime for VBx?
If this is not yet possible, can any MSFT-ies give us an update on when we might see some bits?
There's no release of VB (or C#) that is hostable via the DLR hosting APIs. In general the DLR hosting APIs, and the possibility of getting more MS created languages to support them, are tenatively thought to be post-Dev10. So it won't happen anytime in the short term.