What dynamic asynchronous web server framework to use?

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Should I use flask or Quart or just crossbar to serve dynamic and asynchronous web page ? I need websocket with RPC and PubSub.

I usually work on database with sqlalchemy , and I like brython instead of javascript. I'd like to avoid Node.js if possible.

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Michael Cole On

You can find a list of implementations here

I'm planning to use Node.js and the Crossbar.io documentation is very helpful. Seems like a good choice.